Kajian Literatur tentang Pelayanan Farmasi Klinik dalam Pencegahan Medication Error

Hesti Burhan

doi:10.47134/phms.v3i3.644

Authors

Hesti Trisnianti Burhan Universitas Khairun

DOI:

https://doi.org/10.47134/phms.v3i3.644

Keywords:

Pelayanan Farmasi Klinik, Medication Error, Patient Safety, Drug Related Problems, Medication

Abstract

Penelitian ini bertujuan untuk mengkaji peran pelayanan farmasi klinik dalam pencegahan medication error melalui analisis berbagai hasil penelitian yang relevan. Metode yang digunakan adalah penelitian kualitatif dengan pendekatan deskriptif melalui studi pustaka. Data diperoleh dari artikel ilmiah, systematic review, randomized controlled trial, observational study, dan berbagai dokumen akademik yang membahas medication error, medication reconciliation, drug related problems, dan pelayanan farmasi klinik. Teknik pengumpulan data dilakukan melalui penelusuran literatur dan analisis dokumen secara sistematis, sedangkan analisis data dilakukan melalui identifikasi tema, reduksi data, kategorisasi konsep, interpretasi temuan, dan penarikan kesimpulan secara induktif. Hasil kajian menunjukkan bahwa pelayanan farmasi klinik berperan penting dalam mencegah medication error melalui medication review, medication reconciliation, identifikasi drug related problems, optimalisasi dosis, edukasi pasien, serta kolaborasi multidisiplin. Intervensi farmasis klinis terbukti mampu menurunkan medication discrepancies, meningkatkan keamanan penggunaan obat, mengurangi adverse drug events, dan meningkatkan efisiensi biaya pelayanan kesehatan pada berbagai setting pelayanan, termasuk rawat inap, rawat jalan, intensive care unit, dan layanan onkologi. Selain itu, perkembangan virtual clinical pharmacy service juga memberikan kontribusi dalam meningkatkan akses pelayanan farmasi klinik di daerah dengan keterbatasan sumber daya. Kesimpulan penelitian ini menunjukkan bahwa pelayanan farmasi klinik merupakan komponen penting dalam sistem keselamatan pasien dan memiliki kontribusi signifikan dalam meningkatkan kualitas penggunaan obat serta mutu pelayanan kesehatan secara berkelanjutan.

References

Allan, J., Webster, E. L., Chambers, B., & Nott, S. (2021). This is streets ahead of what we used to do: Staff perceptions of virtual clinical pharmacy services in rural and remote Australian hospitals. BMC Health Services Research, 21(1). https://doi.org/10.1186/s12913-021-07328-w

Bech, C. F., Kart, T., Kjeldsen, L. J., Petersen, M., & Andersen, T. R. H. (2024). Development of hospital clinical pharmacy services in Denmark from 2008 to 2023. European Journal of Hospital Pharmacy. https://doi.org/10.1136/ejhpharm-2024-004226

Belotto, M. (2018). Data analysis methods for qualitative research: Managing the challenges of coding, interrater reliability, and thematic analysis. The Qualitative Report. https://doi.org/10.46743/2160-3715/2018.3492

Bingham, A. (2023). From data management to actionable findings: A five phase process of qualitative data analysis. International Journal of Qualitative Methods, 22. https://doi.org/10.1177/16094069231183620

Canning, M., Barras, M. A., McDougall, R., Yerkovich, S., Coombes, I., Sullivan, C. M., & Whitfield, K. (2024). Defining quality indicators, pharmaceutical care bundles and outcomes of clinical pharmacy service delivery using a Delphi consensus approach. International Journal of Clinical Pharmacy. https://doi.org/10.1007/s11096-023-01681-y

Dosunmu, O., Dwinta, E., & Fatimah, F. S. (2026). Interventions on medication administration errors in Nigerian and Indonesian hospitals: A narrative review. Christian Journal for Global Health. https://doi.org/10.15566/kxb1x733

Doyle, L., McCabe, C., Keogh, B., Brady, A., & McCann, M. (2019). An overview of the qualitative descriptive design within nursing research. Journal of Research in Nursing, 25, 443–455. https://doi.org/10.1177/1744987119880234

Giri, S. K. R. P., Basabih, M., & Sigalingging, B. H. (2024). Medication error prevention using Healthcare Failure Mode and Effect Analysis at clinical pharmacy installation. Jurnal Riset Kesehatan, 13(1). https://doi.org/10.31983/jrk.v13i1.10186

Herath, K. B., Rodrigo, U. A. A., Senadheera, G., Samaranayaka, S., & Samaranayake, N. (2021). Impact of selected clinical pharmacy services on medication safety and prescription cost of patients attending a selected primary healthcare setting: A translational experience from a resource limited country. Postgraduate Medical Journal. https://doi.org/10.1136/postgradmedj-2021-140583

Hilgarth, H., Wichmann, D., Baehr, M., Kluge, S., & Langebrake, C. (2023). Clinical pharmacy services in critical care: Results of an observational study comparing ward based with remote pharmacy services. International Journal of Clinical Pharmacy. https://doi.org/10.1007/s11096-023-01559-z

Huang, S., Xiao, J., Wang, Q., Chen, L., Tan, Y., Cheng, Y., Xie, W., & Xu, P. (2025). Clinical pharmacy services in county hospitals in China: Insights from a national cross sectional study. Journal of Evaluation in Clinical Practice. https://doi.org/10.1111/jep.70226

Kalpokaite, N., & Radivojevic, I. (2018). Demystifying qualitative data analysis for novice qualitative researchers. The Qualitative Report. https://doi.org/10.46743/2160-3715/2019.4120

Kassaw, A. T., Tarekegn, G., Zerihun, T. E., Bekalu, A. F., Wondm, S. A., Moges, T., Zewdu, W. S., Tamene, F. B., Mussie, D. A., & Dagnew, S. B. (2026). The magnitude of drug related problems, typology, and predictors among patients admitted to the pediatric intensive care unit: Impact of pharmacist led interventions in Northwest Ethiopia. Therapeutic Advances in Drug Safety. https://doi.org/10.1177/20420986261422800

Li, C., Cui, J., Liang, X., Zhang, L., Guo, X., Xiang, Y., & Liu, A. (2026). Development and evaluation of the pharmacist intervention evaluation system: A modified classification for drug related problems in Chinese tertiary hospitals. Frontiers in Pharmacology. https://doi.org/10.3389/fphar.2026.1808669

Mashni, O., Nazer, L., Khalil, H., Dalbah, M., Tuffaha, H., Rumman, A., & Jaddoua, S. (2021). Impact of clinical pharmacy services on patient management in the chemotherapy infusion clinics: A 5 year study at a comprehensive cancer center. Journal of Pharmacy Practice. https://doi.org/10.1177/08971900211003446

Naseralallah, L., Stewart, D., Price, M., & Paudyal, V. (2023). Prevalence, contributing factors, and interventions to reduce medication errors in outpatient and ambulatory settings: A systematic review. International Journal of Clinical Pharmacy, 45(6), 1343–1358. https://doi.org/10.1007/s11096-023-01626-5

Nguyen, T., Le, D. B. T., Pham, S. T., Lam, N., Le, Q. N. T., Le, T. T. T., Nguyen, T., Nguyen, P. T. M., Nguyen, T. T., Ngo, T., Duong, N., & Le, N. (2025). Drug related problems and clinical pharmacist interventions in prescribing for older outpatients in Vietnam. Pharmaceutical Sciences Asia. https://doi.org/10.29090/psa.2025.04.25.5474

Nott, S., Fleming, C. A., Hawthorn, G., Luscombe, G. M., Allan, J., Webster, E., Coleman, C., Palazzi, K., Dizon, J., Munro, A., & Chambers, B. (2024). A stepped wedge randomised controlled trial assessing the efficacy and patient acceptability of virtual clinical pharmacy in rural and remote Australian hospitals. BMC Health Services Research, 24(1). https://doi.org/10.1186/s12913-024-11740-3

Schepel, L., Kunnola, E., Airaksinen, M., Aronpuro, K., & Kvarnström, K. (2024). Evolution of hospital clinical pharmacy services in Finland in the period 2017 to 2022: The third nationwide follow up survey. European Journal of Hospital Pharmacy. https://doi.org/10.1136/ejhpharm-2024-004312

Shaker, H., Sabry, A., Salah, A., Ragab, G. M., Sedik, N. A., Ali, Z., Magdy, D., & Alkafafy, A. M. (2023). The impact of clinical pharmacists’ medication reconciliation upon patients’ admission to reduce medication discrepancies in the emergency department: A prospective quasi interventional study. International Journal of Emergency Medicine, 16(1). https://doi.org/10.1186/s12245-023-00568-z

Shi, M., Ma, Y., Li, H., Li, F., & Shen, S. (2024). Exploration and practice of introducing the Pharmaceutical Care Network Europe classification system to psychiatric drugs. Journal of Pharmacy Practice. https://doi.org/10.1177/08971900241273200

Sosyal, D., Bektay, M. Y., Acikgoz, N., & Izzettin, F. (2025). Evaluation of clinical pharmacy services in patients receiving antithrombotic treatment in a randomized controlled trial. Scientific Reports, 15(1). https://doi.org/10.1038/s41598-025-25594-0

Togia, A., & Malliari, A. (2017). Research methods in library and information science. https://doi.org/10.5772/intechopen.68749

Zhang, S., Zhang, G., Huang, P., Ren, Y., Lin, B., Shao, Y. F., & Ye, X. L. (2023). Drug related problems in hospitalized patients with chronic kidney diseases and clinical pharmacist interventions. BMC Geriatrics, 23(1). https://doi.org/10.1186/s12877-023-04557-y